RPSA Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91183-50, BS91183-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P08865(Human) P14206(Mouse) P38983(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC, IP, , FC

All Applications: WB:1:1,000-1:2,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100

Background: Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellular matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregulated in aggressive carcinoma. The precursor, which is also identified as p40 ribosome-associated protein, appears to be a multifunctional protein involved in the translational machinery. Laminin-R (also known as colon carcinoma laminin-binding protein) and is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Additionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RPSA polyclonal antibody detects endogenous levels of RPSA protein.

Bioworld Molecular Weight: 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RPSA on different lysates using anti-RPSA antibody at 1/1,000 dilution.
Positive control:
Lane 1: K562
Lane 2: HepG2
Lane 3: A431, ICC staining RPSA in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: 37LRP, LRP/LR, 67LR, LamR, LBP/p40, RPSA, 34/67 kDa laminin receptor, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 37LRP, 40S ribosomal protein SA, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin binding protein, Colon carcinoma laminin-binding protein, LAMBR, Laminin receptor 1, Laminin-binding protein precursor p40, LAMR 1, LamR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, Multidrug resistance associated protein MGr1 Ag, Multidrug resistance associated protein MGr1Ag, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, p40, Ribosomal Protein SA, rpsA, RSSA, SA,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified