PI3 Kinase p110 gamma Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11415-50, MB11415-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P48736

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PI3 Kinase p110 gamma in K562Lysates using PI3 Kinase p110 gamma antibody.

Bioworld Molecular Weight: Calculated MW: 126 kDa; Observed MW: 110 kDa

Specificity: IgG

Alternative Name: PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K

Immunogen: A synthetic peptide of human PI3K-gamma

Conjugate: Unconjugated

Modification: Unmodified