COX4 Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA10537-50, RA10537-100 Citations, Manuals and MSDS Available upon request. Background: cytochrome c oxidase subunit 4I1 (COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB; IF/ICC; FCM; ELISA Species Cross-Reactivity: Human; Mouse; Rat; Monkey GeneID (Human): 1327 SWISS: P13073 Source: Mouse Research Use Only