Atg16L1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90104-50, BS90104-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q676U5(Human) Q8C0J2(Mouse)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB:1:500-2,000

Background: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Plays a role in regulating morphology and function of Paneth cell.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Atg16L1 on Hela and PC-12 cellLysates using anti-Atg16L1 antibody at 1/500 dilution.

Bioworld Molecular Weight: 68/66 kDa

Specificity: Atg16L1 polyclonal antibody detects endogenous levels of Atg16L1 protein.

Alternative Name: ATG16L1, APG16L, A16L1, APG16 like 1, APG16-like 1, APG16L, APG16L beta, ATG16 autophagy related 16 like 1, ATG16 autophagy related 16-like 1 (S. cerevisiae), ATG16A, ATG16L, Atg16l1, Autophagy related protein 16 1, Autophagy-related protein 16-1, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, OTTHUMP00000164391, OTTHUMP00000164393, OTTHUMP00000165876, OTTHUMP00000165877, WD repeat domain 30, WDR30,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified