CA12 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65248-50, BS65248-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: O43570

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IF (paraffin section), ELISA

All Applications: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Background: carbonic anhydrase 12(CA12) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CA XII Polyclonal Antibody detects endogenous levels of CA XII protein.

Bioworld Molecular Weight: ~ 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of NIH-3T3 293T cells using CA XII Polyclonal Antibody diluted at 1：2000, Western blot analysis of lysates from MCF-7 cells, using CA12 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from COLO205 cells using CA12 antibody.

Alternative Name: CA12; Carbonic anhydrase 12; Carbonate dehydratase XII; Carbonic anhydrase XII; CA-XII; Tumor antigen HOM-RCC-3.1.3

Immunogen: The antiserum was produced against synthesized peptide derived from human CA12. AA range:231-280

Conjugate: Unconjugated

Modification: Unmodified