TUSC3 (H153) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2048-50, BS2048-100

Sizes: 50µl, 100µl

Swiss-Prot: Q13454

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TUSC3 (H153) polyclonal antibody detects endogenous levels of TUSC3 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TUSC3 (H153) pAb at 1:500 dilution
Lane 1: PC3 whole cell lysate (40ug)
Lane 2: L02 whole cell lysate (40ug)
Lane 3: A549 whole cell lysate (40ug)
Lane 4: H9C2 whole cell lysate (40ug)
Lane 5: CT26 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of TUSC3 (H153) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Tumor suppressor candidate 3; Magnesium uptake/transporter TUSC3; Protein N33; TUSC3; N33

Immunogen: Synthetic peptide, corresponding to amino acids 122-171 of Human TUSC3.

Conjugate: Unconjugated

Modification: Unmodified