RRAGA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-15366-60, E-AB-15366-120, E-AB-15366-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: RRAGA

Target Synonym: Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1; Rag A; RagA; Ras-related GTP-binding protein A; RRAGA; RRAGA

Research Areas: Cancer, Cell Biology, Metabolism, Microbiology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q7L523

Background: Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human RRAGA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 37kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only