PARP2 Polyclonal Antibody

Catalogue Numbers: BS91019-50, BS91019-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UGN5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB:1:1000~1:2000

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PARP2 polyclonal antibody detects endogenous levels of PARP2 protein.

Extra Notes: Western blot (WB) analysis of PARP2 pAb at 1:1000 dilution
Lane1:SHSY5Y whole cell lysate(40ug)
Lane2:U-87MG whole cell lysate(40ug)
Lane3:The heart tissue lysate of Rat(40ug)
Lane4:H9C2 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 66 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: PARP-2, hPARP-2, ARTD2, ADPRT-2, pADPRT-2, PARP2, ADPRT2, ADPRTL2, ADP ribosyltransferase like 2, ADP-ribosyltransferase diphtheria toxin-like 2, ADPRT 2, ADPRT-2, ADPRT2, ADPRTL 2, ADPRTL 3, ADPRTL2, ADPRTL3, ARTD2, hPARP 2, hPARP-2, hPARP2, NAD(+) ADP ribosyltransferase 2, NAD(+) ADP-ribosyltransferase 2, pADPRT 2, pADPRT-2, pADPRT2, PARP 2, PARP-2, PARP2, PARP2, Poly (ADP ribose) polymerase family member 2, Poly (ADP ribosyl) transferase like 2, poly (ADP-ribose) polymerase 2, Poly [ADP ribose] synthetase 2, Poly [ADP-ribose] polymerase 2, Poly(ADP ribose) synthetase, Poly[ADP-ribose] synthase 2,

Immunogen: Synthetic peptide, corresponding to Human PARP2.

Conjugate: Unconjugated

Modification: Unmodified