Kif 7 Monoclonal Antibody (3F8)

Size: 50μL, 100μL

Catalogue Numbers: RA11570-50, RA11570-100

Citations, Manuals and MSDS Available upon request.

Background: kinesin family member 7 (KIF7) Homo sapiens This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: IHC-P; IF/ICC

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 374654

SWISS: Q2M1P5

Source: Mouse

Research Use Only