Phospho-TrkB (Y817) Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40184-50, BS40184-100

Swiss-Prot: Q16620

Host: Rabbit

Phospho-TrkB (Y817) Rabbit Monoclonal Antibody-BS40184

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP,

All Applications: WB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30

Background: The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.

Purification and Purity: Affinity-chromatography

Specificity: Phospho-TrkB (Y817) Antibody detects endogenous levels of Phospho-TrkB (Y817)

Bioworld Molecular Weight: 140kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-TrkB (Y817) expression in SH-SY5Y cell lysate treated with BDNF., Immunohistochemical analysis of paraffin-embedded mouse brain cancer, using Phospho-TrkB (Y817) Antibody.

Alternative Name: NTRK2; gp145-TrkB; Trk-B; TRKB; Tropomyosin-related kinase B; TrkB tyrosine kinase; Tyrosine kinase receptor B;

Immunogen: A synthesized peptide derived from human Phospho-TrkB (Y817)

Modification: Phosphorylated

Conjugate: Unconjugated