DOCK 2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24284-50, RA24284-100

Citations, Manuals and MSDS Available upon request.

Background: dedicator of cytokinesis 2 (DOCK2) Homo sapiens The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: DOCK2; KIAA0209; Dedicator of cytokinesis protein 2

Applications: IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1794

SWISS: Q92608

Source: Rabbit

Research Use Only