ATG7 Rabbit rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20825-50, ES20825-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Alternate Name: Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like protein)

Source: Rabbit

Applications: WB; IHC; IF

Dilution: IHC-p 1:50-300, WB 1:500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Recombinant Protein of ATG7

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 78kD

Human Gene ID: 10533

Human SWISS Prot NO: O95352

Subcellular Location: Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.

Research Use Only