Fatty Acid Synthase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2333-50, ES2333-100

Citations, Manuals and MSDS Available upon request.

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],

Alternate Name: FASN; FAS; Fatty acid synthase

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human Fatty Acid Synthase. AA range:1478-1527

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 273kD

Human Gene ID: 2194

Human SWISS Prot NO: P49327

Subcellular Location: Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research Use Only