FADD Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93254-60, E-AB-93254-120, E-AB-93254-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FADD

Target Synonym: Mort1/F; Mort1/FADD

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF, IP

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q61160

Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95 or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of mouse FADD

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000, IF 1:50-1:200, IP 1:50-1:200

Observed MW: 28KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only