Parathyroid hormone/parathyroid hormone-related peptide receptor rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8604-50, ES8604-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],

Alternate Name: Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic peptide from human protein at AA range: 46-122

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 66kD

Human Gene ID: 5745

Human SWISS Prot NO: Q03431

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only