2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4).

Product information

CAS Number: 115-20-8

Molecular Weight: 149.40

Formula: C2H3Cl3O

Chemical Name: 2,2,2-trichloroethan-1-ol

Smiles: OCC(Cl)(Cl)Cl

InChiKey: KPWDGTGXUYRARH-UHFFFAOYSA-N

InChi: InChI=1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery.

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