GRIK2 (GluR6) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20731-50, ES20731-100

Citations, Manuals and MSDS Available upon request.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],

Alternate Name: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4; EAA4; Glutamate receptor 6; GluR-6; GluR6)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:100-200

Reactivity: Human

Immunogen: Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 103kD

Human Gene ID: 2898

Human SWISS Prot NO: Q13002

Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Research Use Only