NRG1 Polyclonal Antibody

Catalogue Numbers: BS60341-50, BS60341-100

Sizes: 50µl, 100µl

Alternative Name: Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; Neuregulin-1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor; NRG1; GGF, HGL, HRGA, NDF, SMDF

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q02297

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. The NRG1 gene encodes a zinc finger protein which specifically binds to two regions in the upstream activation sequence of the STA1 gene. Nrg1 and its homolog Nrg2 function as negative regulators of invasive growth and as repressors of FLO11, which encodes a cell surface glycoprotein required for invasive growth.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.

Bioworld Molecular Weight: ~ 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of NRG1 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: A549 whole cell lysate
Lane 3: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human NRG1.

Conjugate: Unconjugated

Modification: Unmodified