Cathepsin D Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40113-50, BS40113-100

Swiss-Prot: P07339

Host: Rabbit

Cathepsin D Rabbit Monoclonal Antibody-BS40113

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:20

Background: This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Purification and Purity: Affinity-chromatography

Specificity: Cathepsin D Antibody detects endogenous levels of total Cathepsin D

Bioworld Molecular Weight: 46kDa/28kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cathepsin D expression in (1) MCF-7 cell lysate; (2) SKBR-3 cell lysate., Immunohistochemical analysis of paraffin-embedded human ovarian cancer, using Cathepsin D Antibody.

Alternative Name: CATD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311

Immunogen: A synthesized peptide derived from human Cathepsin D

Modification: Unmodified

Conjugate: Unconjugated