M3K12 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33183-50, RA33183-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase kinase kinase 12 (MAP3K12) Homo sapiens This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7786

Protein MW (KDa): 94

SWISS: Q12852

Source: Rabbit

Research Use Only