CEP85 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES17522-50, ES17522-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Alternate Name: Centrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21)

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human CEP85 AA range: 267-317

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 64793

Human SWISS Prot NO: Q6P2H3

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Nucleus, nucleolus. Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856).

Research Use Only