β-Catenin Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1065-50, EM1065-100

Citations, Manuals and MSDS Available upon request.

Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.

Alternate Name: b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:1, 000 IHC 1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 92kDa

Human Gene ID: 1499

Human SWISS Prot NO: P35222

Subcellular Location: Cell junction,  Cell membrane,  Cell projection,  Cytoplasm,  Cytoskeleton,  Membrane,  Nucleus,  Synapse

Research Use Only