MICU1 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22114-60, E-AB-22114-120, E-AB-22114-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MICU1

Target Synonym: Allergen Hom s 4; ara CALC; atopy related autoantigen; atopy related autoantigen CALC; Atopy-related autoantigen CALC; CALC; calcium binding atopy related autoantigen 1; Calcium uptake protein 1; calcium uptake protein 1; mitochondrial; Calcium-binding atopy-related autoantigen 1; CBARA1; EFHA3; FLJ12684; MICU1; MICU1; mitochondrial; mitochondrial calcium uptake 1; MPXPS

Research Areas: Cancer, Metabolism, Immunology, Signal Transduction

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-p, IF

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:4E7

UNIProt ID: Q9BPX6

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300

Observed MW: 55kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only