BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM.

Product information

CAS Number: 101155-02-6

Molecular Weight: 257.27

Formula: C13H12FN5

Chemical Name: 9-[(2-fluorophenyl)methyl]-N-methyl-9H-purin-6-amine

Smiles: CNC1=NC=NC2=C1N=CN2CC1=CC=CC=C1F

InChiKey: MZABAGHILOTTOD-UHFFFAOYSA-N

InChi: InChI=1S/C13H12FN5/c1-15-12-11-13(17-7-16-12)19(8-18-11)6-9-4-2-3-5-10(9)14/h2-5,7-8H,6H2,1H3,(H,15,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 150 mg/mL (583.05 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. BW-A 78U is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release.

Products are for research use only. Not for human use.