RIP3 (phospho-Ser227) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13390-50, ES13390-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],

Alternate Name: Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human

Immunogen: Synthesized phosho peptide around human RIP3 (Ser227)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 56-70kD

Human Gene ID: 11035

Human SWISS Prot NO: Q9Y572

Subcellular Location: Cytoplasm, cytosol. Nucleus. Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection.

Research Use Only