ELK1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90458-50, BS90458-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P19419(Human) P41969(Mouse) A4GTP4(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IP,

All Applications: WB:1:1,000-1:2,000
ICC:1:50-1:200

Background: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ELK1 polyclonal antibody detects endogenous levels of ELK1 protein.

Bioworld Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ELK1 on human lung lysates using anti-ELK1 antibody at 1/1,000 dilution., ICC staining ELK1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: ELK1, ELK 1, Elk1, ELK1 member of ETS oncogene family, ELK1 protein, ELK1, ETS transcription factor, ELK1, ELK2 member of ETS oncogene family, ETS domain containing protein Elk 1, ETS domain containing protein Elk1, ETS domain protein Elk1, ETS domain-containing protein Elk-1, ETS like gene 1, Member of ETS oncogene family, Oncogene Elk1, Tyrosine kinase (ELK1) oncogene,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified