Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors.

Product information

CAS Number: 200959-47-3

Molecular Weight: 1012.17

Formula: C49H69N15O9

Chemical Name: (2S)-6-amino-2-[(Z)-[(2S)-2-[(Z)-[(2S)-5-carbamimidamido-2-[(Z)-[(2S)-2-[(Z)-[(2S)-2-[(Z)-[(2S)-5-carbamimidamido-1-hydroxy-2-[(Z)-(1-hydroxyethylidene)amino]pentylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1-hydroxypentylidene]amino]-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino]hexanimidic acid

Smiles: C/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1C=CC(O)=CC=1)/C(/O)=N/[C@@H](CC1C=CC(O)=CC=1)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CNC2=CC=CC=C12)/C(/O)=N/[C@@H](CCCCN)C(=N)O

InChiKey: YROQVQIJRORFAZ-SKGSPYGFSA-N

InChi: InChI=1S/C49H69N15O9/c1-28(65)59-37(11-6-22-56-48(52)53)43(69)62-40(25-30-15-19-33(67)20-16-30)46(72)63-39(24-29-13-17-32(66)18-14-29)45(71)61-38(12-7-23-57-49(54)55)44(70)64-41(26-31-27-58-35-9-3-2-8-34(31)35)47(73)60-36(42(51)68)10-4-5-21-50/h2-3,8-9,13-20,27,36-41,58,66-67H,4-7,10-12,21-26,50H2,1H3,(H2,51,68)(H,59,65)(H,60,73)(H,61,71)(H,62,69)(H,63,72)(H,64,70)(H4,52,53,56)(H4,54,55,57)/t36-,37-,38-,39-,40-,41-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.