Dkk-1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4292-50, ES4292-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],

Alternate Name: DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 29kD

Human Gene ID: 22943

Human SWISS Prot NO: O94907

Subcellular Location: Secreted

Research Use Only