Histone H3 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22003-60, E-AB-22003-120, E-AB-22003-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Histone H3

Target Synonym: HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: CD20

Application: WB, IHC-p, IF, IP

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:5B1

UNIProt ID: P68431,Q71DI3,P84243

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:100-500, IP 1:100-1:300

Calculated MW: 15kDa

Observed MW: 15kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only