PDE1B Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11382-50, MB11382-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q01064

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PDE1B in rat BrainLysates using PDE1B antibody.

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Specificity: IgG

Alternative Name: PDE1B1; PDES1B; HEL-S-79p

Immunogen: Recombinant protein of human PDE1B

Conjugate: Unconjugated

Modification: Unmodified