a-actinin (4A12) Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1261-50, EM1261-100

Citations, Manuals and MSDS Available upon request.

Background: α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.

Alternate Name: actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody

Source: Mouse

Applications: IHC

Dilution: IHC 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 103kDa

Human Gene ID: 87

Human SWISS Prot NO: P12814

Subcellular Location: Cell junction,  Cell membrane,  Cell projection,  Cytoplasm,  Cytoskeleton,  Membrane

Research Use Only