CLIC1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20785-50, ES20785-100

Citations, Manuals and MSDS Available upon request.

Background: chloride intracellular channel 1 (CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008],

Alternate Name: Chloride intracellular channel protein 1 (Chloride channel ABP; Nuclear chloride ion channel 27; NCC27; Regulatory nuclear chloride ion channel protein; hRNCC)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:100-200

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of CLIC1 AA range: 166-216

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 30kD

Human Gene ID: 1192

Human SWISS Prot NO: O00299

Subcellular Location: Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939).

Research Use Only