Recombinant Cynomolgus CD38/ADP-ribosyl Cyclase 1 Protein (Fc Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSQ050040-10, PKSQ050040-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD38; ADP-ribosyl Cyclase 1

Target Synonym: ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10

UNIProt ID: Q5VAN0

Target Species: Cynomolgus macaques

Expression Host: HEK293 Cells

Fusion Tag: C-Fc

Accession: Q5VAN0

Background: CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

Sequence: Leu44-Ile301

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 57 kDa

Observed MW: 65-95 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only