Nibrin (phospho Ser343) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27826-50, RA27826-100

Citations, Manuals and MSDS Available upon request.

Background: nibrin (NBN) Homo sapiens Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat

GeneID (Human): 4683

Protein MW (KDa): 95

SWISS: O60934

Source: Rabbit

Research Use Only