TTR Mouse Monoclonal Antibody (6E5)

Size: 50μL, 100μL

Catalogue Numbers: RA12131-50, RA12131-100

Citations, Manuals and MSDS Available upon request.

Background: transthyretin (TTR) Homo sapiens This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human

GeneID (Human): 7276

Protein MW (KDa): 16

SWISS: P02766

Source: Mouse

Research Use Only