NQO1 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-93174-60, E-AB-93174-120, E-AB-93174-200 Citations, Manuals and MSDS Available upon request. Abbreviation: NQO1 Target Synonym: DHQU; DIA4; DTD; NMOR1; NMORI; QR1; NQO1 Research Areas: Cancer, Metabolism, Signal Transduction Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: P15559 Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Concentration: 1mg/mL Immunogen: Recombinant fusion protein of human NQO1 Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 Calculated MW: 26kDa/27kDa/30kDa Observed MW: 31kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only