GROγ (N177) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2838-50, BS2838-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P19876

Host: Rabbit

Reactivity: Human

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Growth Regulated Protein gamma (GRO gamma) is a cytokine that may play a role in inflammation and affects endothelial cells in an autocrine fashion. It belongs to the intercrine alpha family (small cytokine c-x-c) (chemokine cxc).Rat CINC2 beta (Cytokine Induced Neutrophil Chemoattractant 2 beta) is a member of the CXC subfamily of chemokines which also includes three other rat CXC chemokines (CINC1, CINC2 alpha, CINC3/MIP2). The rat chemokines CINC show sequence similarity to human GROs and mouse MIP2 but not IL8. Mature CINC2 beta shares 63% amino acid sequence identity with CINC1 and 80% identity to CINC3. Rat CINC2 beta cDNA encodes a 68 amino acid residue protein. The mature recombinant protein has a predicted molecular mass of approximately 7.6 kDa. Based on sequence homology, it has been suggested that CINCs are the rat counterpart of the human GROs.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GROγ (N177) polyclonal antibody detects endogenous levels of GROγ protein.

Bioworld Molecular Weight: ~ 11 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of GROγ (N177) pAb in paraffin-embedded human breast carcinoma tissue at 1:100., Immunohistochemistry (IHC) analyzes of GROγ (N177) pAb in paraffin-embedded human lung macrophages tissue at 1:100.

Alternative Name: C-X-C motif chemokine 3; GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta; GRO3; GROG; SCYB3; CXCL3

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human GROγ.

Conjugate: Unconjugated

Modification: Unmodified