PDX1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63291-60, E-AB-63291-120, E-AB-63291-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PDX1

Target Synonym: PDX1; GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1

Research Areas: Cancer,Cardiovascular,Epigenetics and Nuclear Signaling,Metabolism,Developmental Biology,Signal Transduction,Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P52945

Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Concentration: 1 mg/mL

Immunogen: A synthetic peptide of human PDX1

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 30kDa

Observed MW: 39kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only