alpha 1 FetoProtein Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16050-50, BZ16050-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P02771

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 69 kDa; Observed MW: 69 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of alpha 1 Fetoprotein in mouse liver, mouse serum lysates using alpha 1 Fetoprotein antibody., Immunohistochemistry analysis of paraffin-embedded rat brain using alpha 1 Fetoprotein antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded mouse brain using alpha 1 Fetoprotein antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded mouse brain using alpha 1 Fetoprotein antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AFP. AA range:371-420

Conjugate: Unconjugated

Modification: Unmodified