A-Myb Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21867-50, RA21867-100

Citations, Manuals and MSDS Available upon request.

Background: function:Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: MYBL1; AMYB; Myb-related protein A; A-Myb; Myb-like protein 1

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 4603

Protein MW (KDa): 85

SWISS: P10243

Source: Rabbit

Research Use Only