SLC22A17 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16061-60, E-AB-16061-120, E-AB-16061-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SLC22A17

Target Synonym: 24p3 receptor; 24p3R; BOCT; BOIT; Brain type organic cation transporter; Brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; Neutrophil gelatinase associated lipocalin receptor; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; OTTHUMP00000082690; OTTHUMP00000082691; Potent brain type organic ion transporter; S22AH; Slc22a17; Solute carrier family 22 member 17; Solute carrier family 22 organic cation transporter member 17

Research Areas: Cancer, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8WUG5

Background: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human SLC22A17

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Calculated MW: 56kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only