Superoxide Dismutase 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11653-50, MB11653-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P00441

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 16 kDa; Observed MW: 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Superoxide Dismutase 1 in K562, rat Brain, C6, 3T3, Hela lysates using Superoxide Dismutase 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Superoxide Dismutase 1 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Immunogen: A synthetic peptide of human Superoxide Dismutase 1

Conjugate: Unconjugated

Modification: Unmodified