Myosin Heavy Chain Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1058-50, EM1058-100

Citations, Manuals and MSDS Available upon request.

Background: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.

Alternate Name: Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm (2)2, l (2)36Ae, l (2)k10423, l (2)M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp

Source: Mouse

Applications: IHC, IF

Dilution: IHC 1:200 IF 1:100

Reactivity: Human, Mouse, Rat, Fruit Fly, Nematode

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 220kDa

Human Gene ID: 4619

Human SWISS Prot NO: P12882

Subcellular Location: Cytoplasm,  Thick filament

Research Use Only