Aggrecan Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS66114-50, BS66114-100

Sizes: 50µl, 100µl

Swiss-Prot: P16112

Host: Rabbit

Reactivity: Rat

Applications: IHC

Background: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Aggrecan polyclonal antibody detects endogenous levels of Aggrecan protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry of paraffin-embedded Rat cartilage using Aggrecan pAb at dilution of 1:50 (40x lens).

Bioworld Molecular Weight: ~ 261 kDa

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Alternative Name: ACAN; AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; aggrecan

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-575 of human Aggrecan (NP_037359.3).

Conjugate: Unconjugated

Modification: Unmodified