#1 Bottle Brand2 1 Wide-Neck Bottle Clinically Proven¹ Reduces Colic and Discomfort Designed to Reduce Gas Airflex Venting System Reduces Air Ingestion Ribbed Texture Prevents Nipple Collapse for Uninterrupted Feeding Fewer Part For Easy Cleaning and Assembly BPA Free 1 Months + Clinically proven¹ Clinical studies have shown that the Philips Avent bottle reduces colic and fussing. Fussing is significantly reduced at night as babies fed with Philips Avent anti-colic bottles experienced 60% less fussing than babies fed with a leading competitor's vented bottle. What colic is, and how it affects babies Colic is caused in part by swallowing air while feeding, which creates discomfort in a baby's digestive system. Symptoms include crying, fussing, gassiness and spit-up. Unique Airflex venting system Our clinically-proven Airflex venting system is designed to reduce colic and gas. The nipple shape allows secure latch and the ribbed texture helps prevent collapse for uninterrupted, comfortable feeding. As your baby feeds, the valve integrated into the nipple flexes to allow air into the bottle to prevent vacuum build up and vents it towards the back of the bottle. It keeps air in the bottle and away from baby's tummy to help reduce gas, spit-up and burping. Easy to clean With its wide neck and fewer parts, our bottle is easier to assemble and to clean quickly and thoroughly. At 2 weeks of age, babies fed with a Philips Avent bottle showed a trend to less colic compared to a conventional bottle and a significant reduction in fussing at night compared to babies fed with another leading bottle. #1 bottle brand in America.