HGK Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11367-50, RA11367-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 9448

SWISS: O95819

Source: Mouse

Research Use Only