PE/Elab Fluor® 594 Anti-Mouse CD80 Antibody [16-10A1]

Size: 100μg

Catalogue Number: E-AB-F0992UP-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD80

Target Synonym: T-lymphocyte activation antigen CD80, Cd80, Activation B7-1 antigen, B7,

Conjugation: PE/Elab Fluor® 594

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Armenian Hamster IgG

Clone No.: 16-10A1

UNIProt ID: Q00609

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09853P

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 12519

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag