JAK2 (6B4) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3307-50, MB3307-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O60674

Host: Mouse

Reactivity: Human, Rat, Mouse

Applications: IHC-P

All Applications: IHC: 1/50-1/100

Background: Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: -

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Breast Carcinoma Tissue using JAK2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using JAK2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Immunogen: Synthetic peptide conjugated to KLH.

Conjugate: Unconjugated

Modification: Unmodified