CDC42EP1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90274-50, BS90274-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q00587(Human)

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB:1:1,000-1:2,000

Background: MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CDC42EP1 on differentLysates using anti-CDC42EP1 antibody at 1/1,000 dilution. Positive control: Lane 1: HUVEC Lane 2: Hela

Bioworld Molecular Weight: 60 kDa

Specificity: CDC42EP1 polyclonal antibody detects endogenous levels of CDC42EP1 protein.

Alternative Name: CDC42EP1, 55 kDa bone marrow stromal/endothelial cell protein, Binder of Rho GTPases 5, Bone marrow stromal/endothelial cell protein, 55-KD, BORG 5, BORG5, BORG5, CDC42 effector protein (Rho GTPase binding) 1, Cdc42 effector protein 1, Cdc42ep1, CEP 1, CEP1, MGC15316, MSE 55, MSE55, OTTHUMP00000028709, Serum constituent protein, Serum protein MSE55,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified