Phospho-STAT3 (Y705) Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40378-50, BS40378-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P40763

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP,

All Applications: WB 1:5000~1:10000 IHC 1:50~1:100 ICC/IF 1:50~1:000 IP 1:30

Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Phospho-STAT3 (Y705) Antibody detects endogenous levels of total Phospho-STAT3 (Y705)

Bioworld Molecular Weight: 88kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-STAT3 (Tyr705) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with IFN-a., Immunohistochemical analysis of paraffin-embedded human pancreas, using Phospho-STAT3 (Y705) Antibody., Immunofluorescent analysis of HeLa cells treated with IFN-alpha, using Phospho-STAT3 (Y705) Antibody.

Alternative Name: APRF; Stat3; HIES; Acute-phase response factor;

Immunogen: A synthesized peptide derived from human STAT3

Conjugate: Unconjugated

Modification: Phosphorylated